Geodesic
The influence of $\mathrm{pH}$ on interaction of $\mathrm{CuTOEPyP4}$ with $\mathrm{DNA}$
Proceedings of the Yerevan State University. Physical and mathematical sciences, no. 3 (2008), pp. 97-100 
Y. B. Dalyan; I. V. Vardanyan. The influence of $\mathrm{pH}$ on interaction of $\mathrm{CuTOEPyP4}$ with $\mathrm{DNA}$. Proceedings of the Yerevan State University. Physical and mathematical sciences, no. 3 (2008), pp. 97-100. http://geodesic.mathdoc.fr/item/UZERU_2008_3_a13/
@article{UZERU_2008_3_a13,
     author = {Y. B. Dalyan and I. V. Vardanyan},
     title = {The influence of $\mathrm{pH}$ on interaction of $\mathrm{CuTOEPyP4}$ with $\mathrm{DNA}$},
     journal = {Proceedings of the Yerevan State University. Physical and mathematical sciences},
     pages = {97--100},
     year = {2008},
     number = {3},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/UZERU_2008_3_a13/}
}
TY  - JOUR
AU  - Y. B. Dalyan
AU  - I. V. Vardanyan
TI  - The influence of $\mathrm{pH}$ on interaction of $\mathrm{CuTOEPyP4}$ with $\mathrm{DNA}$
JO  - Proceedings of the Yerevan State University. Physical and mathematical sciences
PY  - 2008
SP  - 97
EP  - 100
IS  - 3
UR  - http://geodesic.mathdoc.fr/item/UZERU_2008_3_a13/
LA  - ru
ID  - UZERU_2008_3_a13
ER  - 
%0 Journal Article
%A Y. B. Dalyan
%A I. V. Vardanyan
%T The influence of $\mathrm{pH}$ on interaction of $\mathrm{CuTOEPyP4}$ with $\mathrm{DNA}$
%J Proceedings of the Yerevan State University. Physical and mathematical sciences
%D 2008
%P 97-100
%N 3
%U http://geodesic.mathdoc.fr/item/UZERU_2008_3_a13/
%G ru
%F UZERU_2008_3_a13

Voir la notice de l'article provenant de la source Math-Net.Ru

The interaction of $\mathrm{Cu(II)}$-meso-tetra-($\mathrm{4N}$-hydroxyethylpyridyl)porphyrim ($\mathrm{CuTOEPyP4}$) with $\mathrm{DNA}$ at different $\mathrm{pH}$ was studied by methods of spectrophotometry and circular dichroism. It was shown that these porphyrins bind to $\mathrm{DNA}$ preferably via intercalation. The calculations show that the constant of binding of $\mathrm{CuTOEPyP4}$ with $\mathrm{DNA}$ strongly depend upon the $\mathrm{pH}$.

[1] M. Aasanka, T. Kurimura, H. Toya, K. Ogaki, Y. Kato, “Anti-HIV activity of protoporphyrin”, AIDS, 3:6 (1989), 403–404 | DOI

[2] D. W. Dixon, L. G. Marzilli, R. F. Schinazi, “Porphyrins as Agents against the Human Immunodeficiency Virus”, Ann. NY Acad. Sci., 616 (1990), 511–519 | DOI

[3] M. J. Carvlin, N. Datta-Gupta, R. J. Fiel, “Circular dichroism spectroscopy of a cationic porphyrin bound to DNA”, Biochem. Biophys. Res. Commun., 108 (1982), 66–73 | DOI

[4] R.F. Pasternack, E.J. Gibbs, “Porphyrin and metalloporphyrin interactions with nucleic acids”, Metal Ions in Biological Systems, 33 (1996), 367–397

[5] Y. B. Dalyan, S. G. Haroutiunian, G. V. Ananyan, V. I. Vardanyan, D. Y. Lando, V. N. Madakyan, R. K. Kazaryan, L. Messory, P. Orioli, A. S. Benight, “Interactions of Meso-tetra-($4$-$\mathrm{N}$-oxyethylpyridyl) Porphyrin, Its $3$-$\mathrm{N}$ Analog and Their Metallocomplexes with Duplex DNA”, J. Biomol. Struct. Dyn., 18:5 (2001), 677–687 | DOI

[6] D. Yu. Lando, S. G. Haroutiunian, Y. B. Dalyan, A. M. Kulba, P. Orioli, R. Mangani, A. A. Akhrem, “Theoretical and Experimental Study of DNA Helix-Coil Transition in Acidic and Alkaline Medium”, J. Biomol. Struct. Dyn., 12:2 (1994), 355–363 | DOI

[7] J. J. Correia, J. B. Chaires, “Analysis of drug-DNA binding isotherms: A Monte Carlo approach”, Methods in Enzymology, 240 (1994), 593–614 | DOI