The influence of peripheral substituents on interaction of porphyrins with DNA
Proceedings of the Yerevan State University. Physical and mathematical sciences, no. 3 (2006), pp. 40-45.

Voir la notice de l'article provenant de la source Math-Net.Ru

The interaction of meso-tetra-(3N-pyridyl)porphyrins with different peripheral substituents was studied by methods of spectrophotometry and circular dichroism. It was shown that for less concentration these porphyrins bind to DNA preferably via intercalation. The binding constants ($K_b$) and the number of binding sites per base pairs ($n$) were calculated by Correia and co-authors’ method.
@article{UZERU_2006_3_a5,
     author = {L. R. Aloyan and G. V. Ananyan and V. I. Vardanyan and Y. B. Dalyan},
     title = {The influence of peripheral substituents on interaction of porphyrins with {DNA}},
     journal = {Proceedings of the Yerevan State University. Physical and mathematical sciences},
     pages = {40--45},
     publisher = {mathdoc},
     number = {3},
     year = {2006},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/UZERU_2006_3_a5/}
}
TY  - JOUR
AU  - L. R. Aloyan
AU  - G. V. Ananyan
AU  - V. I. Vardanyan
AU  - Y. B. Dalyan
TI  - The influence of peripheral substituents on interaction of porphyrins with DNA
JO  - Proceedings of the Yerevan State University. Physical and mathematical sciences
PY  - 2006
SP  - 40
EP  - 45
IS  - 3
PB  - mathdoc
UR  - http://geodesic.mathdoc.fr/item/UZERU_2006_3_a5/
LA  - ru
ID  - UZERU_2006_3_a5
ER  - 
%0 Journal Article
%A L. R. Aloyan
%A G. V. Ananyan
%A V. I. Vardanyan
%A Y. B. Dalyan
%T The influence of peripheral substituents on interaction of porphyrins with DNA
%J Proceedings of the Yerevan State University. Physical and mathematical sciences
%D 2006
%P 40-45
%N 3
%I mathdoc
%U http://geodesic.mathdoc.fr/item/UZERU_2006_3_a5/
%G ru
%F UZERU_2006_3_a5
L. R. Aloyan; G. V. Ananyan; V. I. Vardanyan; Y. B. Dalyan. The influence of peripheral substituents on interaction of porphyrins with DNA. Proceedings of the Yerevan State University. Physical and mathematical sciences, no. 3 (2006), pp. 40-45. http://geodesic.mathdoc.fr/item/UZERU_2006_3_a5/

[1] Dalyan E.B., Biofizika, 47:2 (2002), 253–258

[2] Dalyan Y.B., Haroutiunian S.G., Ananyan G.V., Vardanyan V. I., Lando D.Y., Madakyan V.N., Kazaryan R.K., Messory L., Orioli P., Benight A.S., “Interactions of Meso-tetra-(4-N-oxyethylpyridyl) Porphyrin, Its 3-N Analog and Their Metallocomplexes with Duplex DNA”, Journal of Biomolecular Structure Dynamics, 18:5 (2001), 677–687 | DOI

[3] Fiel R.J., Howard J.C., Mark E.H., Datta-Gupta N., “Interaction of DNA with a porphyrin ligand: evidence for intercalation”, Nucleic Acids Res., 1979, no. 6, 3093–3118 | DOI

[4] Pasternack R.F., Gibbs E.J., “Porphyrin and metalloporphyrin interactions with nucleic acids”, Metal ions in Biological Systems, 1996, no. 33, 367–397

[5] Aasanka M., Kurimura T., Toya H., OgakI K., Kato Y., “Anti-HIV activity of protoporphyrin”, AIDS, 3 (1989), 403–404 | DOI

[6] Dixon D.W., Schinazi R.F., Marzilli L.G., “Porphyrins as Agents against the Human Immunodeficiency Virus”, Ann. NY Acad. Sci., 616 (1990), 511 | DOI

[7] Carvlin M.J., Datta-Gupta N., Fiel R.J., “Circular dichroism spectroscopy of a cationic porphyrin bound to DNA”, Biochem. Biophys. Res. Commun., 108:1 (1982), 66–73 | DOI

[8] Correia J.J., Chaires J.B., “Analysis of drug-DNA binding isotherms: A Monte Carlo approach”, Methods in Enzymology, 240 (1994), 593–614 | DOI