Geodesic
Kinetics of the amino acid uptake by normal and transformed cells
Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali, Série 8, Tome 82 (1988) no. 3, pp. 581-588

Voir la notice de l'article provenant de la source Biblioteca Digitale Italiana di Matematica

HeLa cells, normal rat kidney (NRK) cells and NRK cells transformed with Rous sarcoma virus (RSV) were used to investigate the incorporation of $^{3}H$-leucine, $^{3}H$-glutamate and $^{3}H$-aspartate. Unlike HeLa cells, which are characterized by uniphasic kinetics of uptake of these amino acids, both normal and virus-tranformed NRK cells show two "waves" of uptake: one rapid, the other slow. These waves change in their quantitative proportion when comparing normal and transformed cells. In transformed cells, while the slow wave of leucine and glutamate uptakes is extremely decreased, the rapid wave of glutamate uptake tends to disappear at all. In general, the level of incorporation of aspartate is very low. Anyway, transformation facilitates the rapid wave of penetration of this amino acid. In HeLa cells, the glutamate uptake is strikingly facilitated by carbon dioxide. 
@article{RLINA_1988_8_82_3_a23,
     author = {Eremenkow, Tamilla and Menna, Tonino and Buono, Catello and Fam\`a, Maria and Volpe, Pietro},
     title = {Kinetics of the amino acid uptake by normal and transformed cells},
     journal = {Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali},
     pages = {581--588},
     publisher = {mathdoc},
     volume = {Ser. 8, 82},
     number = {3},
     year = {1988},
     language = {en},
     url = {http://geodesic.mathdoc.fr/item/RLINA_1988_8_82_3_a23/}
}
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Eremenkow, Tamilla; Menna, Tonino; Buono, Catello; Famà, Maria; Volpe, Pietro. Kinetics of the amino acid uptake by normal and transformed cells. Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali, Série 8, Tome 82 (1988) no. 3, pp. 581-588. http://geodesic.mathdoc.fr/item/RLINA_1988_8_82_3_a23/