Mathematical model of cellular transport network self-organization and~functioning

K. A. Novikov ; A. A. Romanyukha ; A. N. Gratchev ; J. G. Kzhyshkowska ; O. A. Melnichenko

Matematičeskoe modelirovanie, Tome 27 (2015) no. 3, pp. 49-62.

Résumé

Contemporary cell investigation methods allowed molecular transport mechanisms of intracellular substances and cell components to be described. Analysis of completeness and consistency of existent data of transport network nature and its utilization is a problem of mathematical modeling. Self-organization of the cell transport network and transport of the cargo and organelles upon it are modeled in this work by the examples of mitotic spindle formation, retrograde axonal transport and lipid transport.

Détail

Mots-clés : cell, microtubules.
Keywords: metabolism, transport network, vesicles, endosomes, self-organization

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