Mathematical model of the humoral immune response: focusing on Th17 autoimmunity

S. R. Kuznetsov

Matematičeskaâ biologiâ i bioinformatika, Tome 10 (2015) no. 2, pp. 455-472.

Résumé

This work is devoted to development of mathematical model, describing processes of Th and B lymphocyte proliferation and differentiation, as well as IFN-$\gamma$, IL-2, IL-4 and IL-21 cytokine secretion. New approaches are suggested, allowing more accurate modelling. Special attention paid to Th17 lymphocyte impact to effect of plasma cells and IgM and IgG antibody level increasing.

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