Geodesic
The Application of Model Reduction Methods to the Construction of the Composite Model of Apoptotic Pathways
Matematičeskaâ biologiâ i bioinformatika, Tome 7 (2012) no. 2, pp. 572-588.

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We propose a new approach to composition of mathematical models of biological systems, based on their reduction. This approach has been tested on the example of two apoptosis models describing pro- and anti-apoptotic (activation of NF-$\kappa$B) pathways of CD95. 
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Elena O. Kutumova; Andrey Y. Zinovyev; Ruslan N. Sharipov; Fedor A. Kolpakov. The Application of Model Reduction Methods to the Construction of the Composite Model of Apoptotic Pathways. Matematičeskaâ biologiâ i bioinformatika, Tome 7 (2012) no. 2, pp. 572-588. http://geodesic.mathdoc.fr/item/MBB_2012_7_2_a7/

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