Geodesic
Development of mathematical methods and software for protein's functional sites detection
Matematičeskaâ biologiâ i bioinformatika, Tome 5 (2010) no. 2, pp. 162-175.

Voir la notice de l'article provenant de la source Math-Net.Ru

The program for analysis of protein's surfaces with the purpose of functional site detection has been designed. The program allows building the molecular protein's surfaces, detecting the pockets, canals and cavities and carrying out the analysis of hydrophobic areas and charge distribution on the surfaces. Using this program one of functional sites of human G-CSF has been defined and its low-molecular functional analog has been forecasted. 
@article{MBB_2010_5_2_a8,
     author = {I. V. Shutova and V. P. Golubovich},
     title = {Development of mathematical methods and software for protein's functional sites detection},
     journal = {Matemati\v{c}eska\^a biologi\^a i bioinformatika},
     pages = {162--175},
     publisher = {mathdoc},
     volume = {5},
     number = {2},
     year = {2010},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/MBB_2010_5_2_a8/}
}
TY  - JOUR
AU  - I. V. Shutova
AU  - V. P. Golubovich
TI  - Development of mathematical methods and software for protein's functional sites detection
JO  - Matematičeskaâ biologiâ i bioinformatika
PY  - 2010
SP  - 162
EP  - 175
VL  - 5
IS  - 2
PB  - mathdoc
UR  - http://geodesic.mathdoc.fr/item/MBB_2010_5_2_a8/
LA  - ru
ID  - MBB_2010_5_2_a8
ER  - 
%0 Journal Article
%A I. V. Shutova
%A V. P. Golubovich
%T Development of mathematical methods and software for protein's functional sites detection
%J Matematičeskaâ biologiâ i bioinformatika
%D 2010
%P 162-175
%V 5
%N 2
%I mathdoc
%U http://geodesic.mathdoc.fr/item/MBB_2010_5_2_a8/
%G ru
%F MBB_2010_5_2_a8
I. V. Shutova; V. P. Golubovich. Development of mathematical methods and software for protein's functional sites detection. Matematičeskaâ biologiâ i bioinformatika, Tome 5 (2010) no. 2, pp. 162-175. http://geodesic.mathdoc.fr/item/MBB_2010_5_2_a8/

[1] Severin E. S., Aleinikova T. L., Osipov E. V., Silaeva S. A., Biologicheskaya khimiya, MIA, 2008

[2] DesJarlais R. L., Sheridan R. P., Seibel G. L., Dixon J. S., Kuntz I. D. and Venkataraghavan R., J. Med. Chem., 31:4 (1988), 722–729 | DOI

[3] Hendlich M., Rippmann F., Barnickel G., J. Mol. Graph. Model., 15 (1997), 359–363 ; 389 | DOI

[4] Kuntz I. D., Blaney J. M., Oatley S. J., Langridge R. and Ferrin T. E., J. Mol. Biol., 161 (1982), 269–88 | DOI

[5] Laskowski R. A., Luscombe N. M., Swindells M. B. and Thornton J. M., Protein Sci., 5 (1996), 2438–2452

[6] Glaser F., Morris R. J., Najmanovich R. J., Laskowski R. A. and Thornton J. M., Proteins, 62:2 (2006), 479–488 | DOI

[7] Yu J., Zhou Y., Tanaka I. and Yao M., Bioinformatics, 26:1 (2010), 46–52 | DOI

[8] Zvelebil M. J., Baum J. O., Understanding Bioinformatics, Garland Science, 2008 | Zbl

[9] Richmond T. J., J. Mol. Biol., 178 (1984), 63–89 | DOI

[10] Perrot G., Cheng B., Gibson K. D., Vila J., Palmer K. A., Nayeem A., Maigret B. and Scheraga H. A., J. Comp. Chem., 13 (1992), 1–11 | DOI | MR

[11] Gogonea V., Osawa E., J. Mol. Struct. (THEOCHEM), 311 (1994), 305–324 | DOI

[12] Sridharan S., Nicholls A., Sharp K. A., J. Comp. Chem., 16:8 (1994), 1038 | DOI

[13] Connolly M. L., J. Appl. Crystallogr., 16 (1983), 548–558 | DOI

[14] Connolly M. L., Science, 221 (1983), 709–713 | DOI

[15] Lee B., Richards F. M., J. Mol. Biol., 55 (1971), 379–400 | DOI

[16] Richards F. M., Ann. Rev. Biophys. Bioeng., 6 (1977), 151–176 | DOI

[17] Michael L., Connolly. Molecular Surfaces: A Review, , (data obrascheniya: 05.12.2010) http://www.netsci.org/ Science/Compchem/feature14.html

[18] Zefirov Yu. V., Zorkii P. M., Zhurn. struktur. khimii, 15:1 (1974), 118–122

[19] Laurie A. T. R., Jackson R. M., Current Protein and Peptide Science, 7 (2006), 395–406 | DOI

[20] Laurie A. T., Jackson R. M., Bioinformatics, 21 (2005), 1908–1916 | DOI

[21] Ruppert J., Welch W., Jain A. N., Protein Sci., 6 (1997), 524–533 | DOI

[22] An J., Totrov M., Abagyan R., Mol. Cell Proteom., 4 (2005), 752–761 | DOI

[23] Laskowski R. A., J. Mol. Graph., 13 (1995), 323–330 ; 307–308 | DOI

[24] Shutova I. V., Gribovskaya O. V., Tsyganova O. V., Golubovich V. P., Doklady NAN Belarusi, 53:1 (2009), 79–84

[25] Shutova I. V., Golubovich V. P., Bioregulyatory: issledovanie i primenenie, Sbornik nauchnykh statei, v. 2, eds. F. A. Lakhvich, Belorusskaya nauka, Minsk, 2008, 186–191

[26] Martinovich V., Gribovskaya O., Shutova I., Golubovich V., Journal of Peptide Science, 16:S2 (2010), 165

[27] Lu H. S., Boone T. C., Souza L. M., Lai P. H., Arch. Biochem. Biophys., 268 (1989), 81 | DOI

[28] Young D. C., Protein Science, 6 (1997), 1228–1236 | DOI

[29] Golubovich V. P., Goranov V. A., Kovalenko A. P., Melnik O. V., Shutova I. V., Peptid, obladayuschii rostostimuliruyuschei aktivnostyu granulotsitarnogo koloniestimuliruyuschego faktora cheloveka, Patent No 2385875RU, 2010

[30] Welte K., Gabrilove J., Bronchud M. H., Platzer E. and Morstyn G., Blood, 88 (1996), 1907

[31] Davydovskii A. G., Klimkovich V. A., Aktualnye problemy gematologii i transfuziologii, Materialy nauchnykh trudov VI s'ezda gematologov i transfuziologov Respubliki Belarus, Minsk, 2007, 214–216

[32] Davydovskii A. G., Klimkovich V. A., Moskva V. V., Dmitriev V. V., Aktualnye problemy gematologii i transfuziologii, Materialy nauchnykh trudov VI s'ezda gematologov i transfuziologov Respubliki Belarus, Minsk, 2007, 76–77