Representation theoretic patterns in three dimensional Cryo-Electron Microscopy I: The intrinsic reconstitution algorithm
Annals of mathematics, Tome 174 (2011) no. 2, pp. 1219-1241.

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In this paper, we reveal the formal algebraic structure underlying the intrinsic reconstitution algorithm, introduced by Singer and Shkolnisky in [S], for determining three dimensional macromolecular structures from images obtained by an electron microscope. Inspecting this algebraic structure, we obtain a conceptual explanation for the admissibility (correctness) of the algorithm and a proof of its numerical stability. In addition, we explain how the various numerical observations reported in that work follow from basic representation theoretic principles.
DOI : 10.4007/annals.2011.174.2.11

Ronny Hadani 1 ; Amit Singer 2

1 Department of Mathematics<br/>The University of Texas at Austin<br/>Austin, TX 78712
2 Department of Mathematics and PACM<br/> Princeton University<br/> Princeton, NJ 08544
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Ronny Hadani; Amit Singer. Representation theoretic patterns in three dimensional Cryo-Electron Microscopy I:  The intrinsic reconstitution algorithm. Annals of mathematics, Tome 174 (2011) no. 2, pp. 1219-1241. doi : 10.4007/annals.2011.174.2.11. http://geodesic.mathdoc.fr/articles/10.4007/annals.2011.174.2.11/

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