Geodesic
Computational determination of the optimal dose of the cis-platinum to maximize the life time of patients diagnosed with cancer.
Mathematica Applicanda, Tome 47 (2019) no. 2, pp. 187-196.

Voir la notice de l'article provenant de la source Annales Societatis Mathematicae Polonae Series

In this work, we present the results of our study over the expected lifetime of the patients diagnosed with relapsed squamous cell lung cancer, which is a subtype of non-small cell lung cancer, treated by cis-platinum. We developed the mathematical model consist of cells sensitive and resistant to cis-platinum. The performed simulations suggest that the best strategy to prolong the patient lifetime after diagnosis is to keep the sensitive cells subpopulation at the constant level instead of killing all of them.
DOI : 10.14708/ma.v47i2.6485
Classification : 92B05
Mots-clés : therapy optimization, cis-platinum, cancer grow, resistance to the drug 
@article{10_14708_ma_v47i2_6485,
     author = {Emilia Koz{\l}owska and Krzysztof Puszynski},
     title = {Computational determination of the optimal dose of the cis-platinum to maximize the life time of patients diagnosed with cancer.},
     journal = {Mathematica Applicanda},
     pages = { 187--196},
     publisher = {mathdoc},
     volume = {47},
     number = {2},
     year = {2019},
     doi = {10.14708/ma.v47i2.6485},
     language = {pl},
     url = {http://geodesic.mathdoc.fr/articles/10.14708/ma.v47i2.6485/}
}
TY  - JOUR
AU  - Emilia Kozłowska
AU  - Krzysztof Puszynski
TI  - Computational determination of the optimal dose of the cis-platinum to maximize the life time of patients diagnosed with cancer.
JO  - Mathematica Applicanda
PY  - 2019
SP  -  187
EP  - 196
VL  - 47
IS  - 2
PB  - mathdoc
UR  - http://geodesic.mathdoc.fr/articles/10.14708/ma.v47i2.6485/
DO  - 10.14708/ma.v47i2.6485
LA  - pl
ID  - 10_14708_ma_v47i2_6485
ER  - 
%0 Journal Article
%A Emilia Kozłowska
%A Krzysztof Puszynski
%T Computational determination of the optimal dose of the cis-platinum to maximize the life time of patients diagnosed with cancer.
%J Mathematica Applicanda
%D 2019
%P  187-196
%V 47
%N 2
%I mathdoc
%U http://geodesic.mathdoc.fr/articles/10.14708/ma.v47i2.6485/
%R 10.14708/ma.v47i2.6485
%G pl
%F 10_14708_ma_v47i2_6485
Emilia Kozłowska; Krzysztof Puszynski. Computational determination of the optimal dose of the cis-platinum to maximize the life time of patients diagnosed with cancer.. Mathematica Applicanda, Tome 47 (2019) no. 2, pp.  187-196. doi : 10.14708/ma.v47i2.6485. http://geodesic.mathdoc.fr/articles/10.14708/ma.v47i2.6485/

Cité par Sources :