Geodesic
The interplay between stochastic gene switching and certain metronomics therapies.
Mathematica Applicanda, Tome 46 (2018) no. 1, pp. 127-136.

Voir la notice de l'article provenant de la source Annales Societatis Mathematicae Polonae Series

In this work I present some preliminary results of the exploration of the interplay between stochastic gene switching and certain metronomics therapies. During the research a simple model of gene-mRNA-protein network subjected to the metronomic therapy was investigated. The results show that the stochastic gene switching process, especially the time expected between successive switching plays a significant role in determining the size of the responding cells fraction.
DOI : 10.14708/ma.v46i1.6392
Classification : 92B05, 34C11, 34D20, 34K60, 92C60.
Mots-clés : stochastic gene switching, pharmacodynamics, metronomics therapy 
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Krzysztof Puszynski. The interplay between stochastic gene switching and certain metronomics therapies.. Mathematica Applicanda, Tome 46 (2018) no. 1, pp.  127-136. doi : 10.14708/ma.v46i1.6392. http://geodesic.mathdoc.fr/articles/10.14708/ma.v46i1.6392/

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