Simultaneous testing procedures of many null hypotheses and their applications in the DNA microarrays analysis
Mathematica Applicanda, Tome 35 (2007) no. 49/08, pp. 84-108 Cet article a éte moissonné depuis la source Annales Societatis Mathematicae Polonae Series

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In our paper, we consider different approaches to the problem of simultaneous testing of many null hypotheses. In this context, we discuss the single-step, the step-down and the step-up procedures of multiple testing. In particular, we are concerned with their properties and applications in the control of the error rates, such as:FW ER, k-FWER, FDP, FDR, pFDR. The mentioned procedures are intensively used in the DNA microarrays analysis, which enables the monitoring of expression levels of many genes simultaneously and is widely applied in recent medical diagnostics, treatment and research.
DOI : 10.14708/ma.v35i49/08.1389
Classification : 62F03 (62P10)
Mots-clés : Multiple hypothesis testing procedures, Familywise error rate, False discovery proportion, False discovery rate, p-values, q-values, DNA microarrays
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Marcin Dudziński; Konrad Furmańczyk. Simultaneous testing procedures of many null hypotheses and their applications in the DNA microarrays analysis. Mathematica Applicanda, Tome 35 (2007) no. 49/08, pp.  84-108. doi: 10.14708/ma.v35i49/08.1389

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