Analysis of multicomponent mixture on the example of the drug ``Pentalgin” by the methods of TLC and IR-Fourier spectrometry
Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 3 (2015), pp. 164-173

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The definition of a qualitative composition of multicomponent drugs "Pentalgin” and "Pentalgin ICN” by TLC and IR-spectrometry is carried out. It is shown that using just TLC or just FT-IR spectrometry does not allow us to identify all the major components. It has been proposed an authentication scheme, which includes the steps of isolating of the test components, their separation by TLC, followed by extraction of components and definition by FTIR spectrometry. The combination of these two techniques allows to separate and identify almost all the most important components of the mixture.
Keywords: FT-IR spectrometry, TLC, combination of methods, pentalgin, qualitative analysis, medicines, tablets, paracetamol, metamezol sodium, hydrochloride drotaverine.
Mots-clés : identification scheme
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     author = {A. L. Lobachev and N. A. Red'kin and Yu. V. Trifonova},
     title = {Analysis of multicomponent mixture on the example of the drug {``Pentalgin{\textquotedblright}} by the methods of {TLC} and {IR-Fourier} spectrometry},
     journal = {Vestnik Samarskogo universiteta. Estestvennonau\v{c}na\^a seri\^a},
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     number = {3},
     year = {2015},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/VSGU_2015_3_a13/}
}
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A. L. Lobachev; N. A. Red'kin; Yu. V. Trifonova. Analysis of multicomponent mixture on the example of the drug ``Pentalgin” by the methods of TLC and IR-Fourier spectrometry. Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 3 (2015), pp. 164-173. http://geodesic.mathdoc.fr/item/VSGU_2015_3_a13/