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Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human in vitro
Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 10 (2015), pp. 143-150 Cet article a éte moissonné depuis la source Math-Net.Ru

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The study of newly synthesized derivatives of 1-adamantane carboxylic acid anilide, 1-adamantanecarboxylic acid (N-adamantyl-1-carboxamide) bromanilide1-adamantanecarboxylic acid (N-(4-bromophenyl) adamantyl-1-carboxamide) on platelet aggregation induced of human in vitro is implemented. A significant effect on platelet aggregation anilide 1-adamantane carboxylic acid, 4-bromanilid 1-adamantanecarboxylic acid observed a tendency to increase its intensity. The ability to affect platelet aggregation correlates with the presence of bromine in the benzene ring. Ascending effect on aggregation can be positioned in a number of investigated solvents: acetone, 2-propanol, ethanol, methanol, dimethylsulfoxide.
Keywords: 1-adamantanecarboxylic acid, induced aggregation, benzene ring, blood, acetone, ethanol, methanol
Mots-clés : dimethylsulfoxide. 
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     title = {Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human in vitro},
     journal = {Vestnik Samarskogo universiteta. Estestvennonau\v{c}na\^a seri\^a},
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     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/}
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A. S. Gil'mutdinova; V. A. Ermokhin; P. P. Purygin; N. A. Klenova. Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human in vitro. Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 10 (2015), pp. 143-150. http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/

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