Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}
Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 10 (2015), pp. 143-150
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The study of newly synthesized derivatives of 1-adamantane carboxylic acid anilide, 1-adamantanecarboxylic acid (N-adamantyl-1-carboxamide) bromanilide1-adamantanecarboxylic acid (N-(4-bromophenyl) adamantyl-1-carboxamide) on platelet aggregation induced of human in vitro is implemented. A significant effect on platelet aggregation anilide 1-adamantane carboxylic acid, 4-bromanilid 1-adamantanecarboxylic acid observed a tendency to increase its intensity. The ability to affect platelet aggregation correlates with the presence of bromine in the benzene ring. Ascending effect on aggregation can be positioned in a number of investigated solvents: acetone, 2-propanol, ethanol, methanol, dimethylsulfoxide.
Keywords:
1-adamantanecarboxylic acid, induced aggregation, benzene ring, blood, acetone, ethanol, methanol
Mots-clés : dimethylsulfoxide.
Mots-clés : dimethylsulfoxide.
@article{VSGU_2015_10_a10,
author = {A. S. Gil'mutdinova and V. A. Ermokhin and P. P. Purygin and N. A. Klenova},
title = {Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}},
journal = {Vestnik Samarskogo universiteta. Estestvennonau\v{c}na\^a seri\^a},
pages = {143--150},
publisher = {mathdoc},
number = {10},
year = {2015},
language = {ru},
url = {http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/}
}
TY - JOUR
AU - A. S. Gil'mutdinova
AU - V. A. Ermokhin
AU - P. P. Purygin
AU - N. A. Klenova
TI - Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}
JO - Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ
PY - 2015
SP - 143
EP - 150
IS - 10
PB - mathdoc
UR - http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/
LA - ru
ID - VSGU_2015_10_a10
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%A N. A. Klenova
%T Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}
%J Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ
%D 2015
%P 143-150
%N 10
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%F VSGU_2015_10_a10
A. S. Gil'mutdinova; V. A. Ermokhin; P. P. Purygin; N. A. Klenova. Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}. Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 10 (2015), pp. 143-150. http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/