Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}
Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 10 (2015), pp. 143-150

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The study of newly synthesized derivatives of 1-adamantane carboxylic acid anilide, 1-adamantanecarboxylic acid (N-adamantyl-1-carboxamide) bromanilide1-adamantanecarboxylic acid (N-(4-bromophenyl) adamantyl-1-carboxamide) on platelet aggregation induced of human in vitro is implemented. A significant effect on platelet aggregation anilide 1-adamantane carboxylic acid, 4-bromanilid 1-adamantanecarboxylic acid observed a tendency to increase its intensity. The ability to affect platelet aggregation correlates with the presence of bromine in the benzene ring. Ascending effect on aggregation can be positioned in a number of investigated solvents: acetone, 2-propanol, ethanol, methanol, dimethylsulfoxide.
Keywords: 1-adamantanecarboxylic acid, induced aggregation, benzene ring, blood, acetone, ethanol, methanol
Mots-clés : dimethylsulfoxide.
@article{VSGU_2015_10_a10,
     author = {A. S. Gil'mutdinova and V. A. Ermokhin and P. P. Purygin and N. A. Klenova},
     title = {Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}},
     journal = {Vestnik Samarskogo universiteta. Estestvennonau\v{c}na\^a seri\^a},
     pages = {143--150},
     publisher = {mathdoc},
     number = {10},
     year = {2015},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/}
}
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A. S. Gil'mutdinova; V. A. Ermokhin; P. P. Purygin; N. A. Klenova. Study of the derivatives of 1-adamantane carboxylic acid to induced platelet aggregation human \emph{in vitro}. Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 10 (2015), pp. 143-150. http://geodesic.mathdoc.fr/item/VSGU_2015_10_a10/