The effects of gastrin-releasing peptide microinjections into the pre-Botzinger complex on the respiratory parameters of rats
    
    
  
  
  
      
      
      
        
Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 6 (2012), pp. 167-173
    
  
  
  
  
  
    
      
      
        
      
      
      
    Voir la notice de l'article provenant de la source Math-Net.Ru
            
              			In the article, the results of investigation of the respiratory effects of gastrin-releasing peptide microjections into the pre-Botzinger complex are presented. It was found that microinjections of neuropeptide induced an increase in respiratory rate, tidal volume, amplitude of diaphragm and external intercostal muscles bursting activity. The statistically significant respiratory responses observed when $10^{-5}$ M of GRP was used, while $10^{-8}$ M of GRP appeared to be sub-threshold and didn't alter the breathing pattern and activity of inspiratory muscles. The suggested mechanisms of action of GRP at the level of pre-Botzinger complex are discussed.
			
            
            
            
          
        
      
                  
                    
                    
                    
                    
                    
                      
Keywords: 
gastrin-releasing peptide, pre-Botzinger complex, respiratory center, bombesin receptors.
                    
                  
                
                
                @article{VSGU_2012_6_a17,
     author = {A. A. Aliev and A. N. Inyushkin},
     title = {The effects of gastrin-releasing peptide microinjections into the {pre-Botzinger} complex on the respiratory parameters of rats},
     journal = {Vestnik Samarskogo universiteta. Estestvennonau\v{c}na\^a seri\^a},
     pages = {167--173},
     publisher = {mathdoc},
     number = {6},
     year = {2012},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/VSGU_2012_6_a17/}
}
                      
                      
                    TY - JOUR AU - A. A. Aliev AU - A. N. Inyushkin TI - The effects of gastrin-releasing peptide microinjections into the pre-Botzinger complex on the respiratory parameters of rats JO - Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ PY - 2012 SP - 167 EP - 173 IS - 6 PB - mathdoc UR - http://geodesic.mathdoc.fr/item/VSGU_2012_6_a17/ LA - ru ID - VSGU_2012_6_a17 ER -
%0 Journal Article %A A. A. Aliev %A A. N. Inyushkin %T The effects of gastrin-releasing peptide microinjections into the pre-Botzinger complex on the respiratory parameters of rats %J Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ %D 2012 %P 167-173 %N 6 %I mathdoc %U http://geodesic.mathdoc.fr/item/VSGU_2012_6_a17/ %G ru %F VSGU_2012_6_a17
A. A. Aliev; A. N. Inyushkin. The effects of gastrin-releasing peptide microinjections into the pre-Botzinger complex on the respiratory parameters of rats. Vestnik Samarskogo universiteta. Estestvennonaučnaâ seriâ, no. 6 (2012), pp. 167-173. http://geodesic.mathdoc.fr/item/VSGU_2012_6_a17/
