Geodesic
Caratteristiche sinaptiche della proiezione callosale alle aree somestesiche (SI e SII) del Gatto
Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali, Série 8, Tome 52 (1972) no. 4, pp. 551-557 Cet article a éte moissonné depuis la source Biblioteca Digitale Italiana di Matematica

Voir la notice de l'article

The synaptic events, induced by transcallosal afferents in somesthetic cortical neurones were studied with intracellular technique in 21 units (14 belonging to SI and 7 to SII), out of a larger sample whose characteristics of transcallosal as well as peripheral reactivity were determined extracellularly. The recordings were obtained from chloralose-anaesthetized, curarized cats by means of glass micropipettes (2M K-citrate or 2.5 M KCl; 10-50 M$\Omega$ in resistance) and DC-, AC-amplifying conventional apparatus. Upon peripheral stimulation each neurone was classified as reactive to small, contralateral (Group I; 5 units) or to wide, ipsi-and contralateral peripheral receptive fields (Group II; 16 units). All neurones were further tested with electrical stimulation of contralateral SI and SII cortical areas. Transcallosal excitatory and inhibitory effects were obtained. The excitatory effects were either small, slowly-rising EPSPs, variable both in time-course and amplitude (11 units), or strong and fast-rising EPSPs (5 units). The former triggered inconsistent and unsteady spike discharges, whereas the latter easily precipitated firing activity, followed in turn by clear-cut secondary IPSPs, just as did peripheral stimulation in both groups of units. Pure inhibitory effects were observed in 5 more neurones, yielding primary IPSPs capable of blocking both spontaneous and evoked discharges. Occasionally, units showing interneuronal-like discharges were found, temporally related to the development of primary IPSPs appearing in the former cells. The latencies of both excitatory and inhibitory slow potentials were consistent with their generation by transcallosal impulses. According to the evidence obtained, it is suggested that most transcallosal excitatory effects might be generated by remote synaptic contacts located at apical dendrite spines, thus modulating the neuronal activity induced by peripheral afferents. The inhibitory effects induced over the callosal route are post-synaptic in nature and might be generated in the cortex itself through interneuronal mediation. 
@article{RLINA_1972_8_52_4_a15,
     author = {Innocenti, Giorgio Maria and Manzoni, Tullio and Spidalieri, Giuseppe},
     title = {Caratteristiche sinaptiche della proiezione callosale alle aree somestesiche {(SI} e {SII)} del {Gatto}},
     journal = {Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali},
     pages = {551--557},
     year = {1972},
     volume = {Ser. 8, 52},
     number = {4},
     language = {it},
     url = {http://geodesic.mathdoc.fr/item/RLINA_1972_8_52_4_a15/}
}
TY  - JOUR
AU  - Innocenti, Giorgio Maria
AU  - Manzoni, Tullio
AU  - Spidalieri, Giuseppe
TI  - Caratteristiche sinaptiche della proiezione callosale alle aree somestesiche (SI e SII) del Gatto
JO  - Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali
PY  - 1972
SP  - 551
EP  - 557
VL  - 52
IS  - 4
UR  - http://geodesic.mathdoc.fr/item/RLINA_1972_8_52_4_a15/
LA  - it
ID  - RLINA_1972_8_52_4_a15
ER  - 
%0 Journal Article
%A Innocenti, Giorgio Maria
%A Manzoni, Tullio
%A Spidalieri, Giuseppe
%T Caratteristiche sinaptiche della proiezione callosale alle aree somestesiche (SI e SII) del Gatto
%J Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali
%D 1972
%P 551-557
%V 52
%N 4
%U http://geodesic.mathdoc.fr/item/RLINA_1972_8_52_4_a15/
%G it
%F RLINA_1972_8_52_4_a15
Innocenti, Giorgio Maria; Manzoni, Tullio; Spidalieri, Giuseppe. Caratteristiche sinaptiche della proiezione callosale alle aree somestesiche (SI e SII) del Gatto. Atti della Accademia nazionale dei Lincei. Rendiconti della Classe di scienze fisiche, matematiche e naturali, Série 8, Tome 52 (1972) no. 4, pp. 551-557. http://geodesic.mathdoc.fr/item/RLINA_1972_8_52_4_a15/

[1] G. M. Innocenti e T. Manzoni, «Rend. Accad. Naz. Lincei, Cl. Sci. fis., mat. nat.», ser. VIII, 49, 431 (1970).

[2] G. M. Innocenti e T. Manzoni, «Rend. Accad. Naz. Lincei, Cl. Sci. fis., mat. nat.», ser. VIII, 51, 254 (1971).

[3] C.-L. Li e S. N. Chou, Inhibitory interneurons in the neocortex. In E. Roberts (Chief Ed.), «Inhibition in the nervous system and gamma-aminobutyric acid», pp. 34-39, Pergamon Press, Oxford (1960).

[4] J. Szentágothai, Architecture of the cerebral cortex. In H. H. Jasper, A. A. Ward e A. Pope (Eds.), «Basic mechanisms of the epilepsies», pp. 13-28, Little, Brown e Co., Boston (1969).

[5] J. Szentágothai, «Bull. Acad. Roy. Med. (Belgique)», VII sér., 10, 475 (1970).

[6] J. Szentágothai, «Acta biol. Sci. hung.», 22, 107 (1971).

[7] O. D. Creutzfeldt, K. Maekawa e L. Hösli, Forms of spontaneous and evoked post-synaptic potentials of cortical nerve cells. In K. Akert e P.G. Waser (Eds.), «Mechanisms of synaptic transmission» (Progress in Brain Research, 31), pp. 265-273, Elsevier, Amsterdam (1969).

[8] E. Fadiga e J.M. Brookhart, «Am. J. Physiol.», 198, 693 (1960).

[9] S. Jacobson e D. A. Pollen, «Science», 161, 1351 (1968).

[10] W. Rall, «J. Neurophysiol.», 30, 1138 (1967).

[11] J. S. Lund e R. D. Lund, «Brain Res.», 17, 25 (1970).

[12] O. D. Creutzfeldt, H. D. Lux e S. Watanabe, Electrophysiology of cortical nerve cells. In D.P. Purpura e M. D. Yahr (Eds.), «The Thalamus», pp. 209-235, Columbia University Press, New York (1966).

[13] M. R. Klee, Different effects on the membrane potential of motor cortex units after thalamic and reticular stimulation. In D. P. Purpura e M. D. Yahr (Eds.), «The Thalamus», pp. 287-322, Columbia University Press, New York (1966).

[14] K. Uchizono, «Nature», 207, 642 (1965).

[15] J. C. Eccles, The physiology of synapses, pp. XI-316, Springer-Verlag, Berlin (1964).