A plasmonic turn-on insulin sensing platform on centimeter scale nanostructure arrays
Nanosistemy: fizika, himiâ, matematika, Tome 15 (2024) no. 2, pp. 300-306.

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We present a plasmonic turn-on biosensing assay for insulin detection via aptamer DNA based on the plasmonic interaction of centimeter scale gold/silver double-layer nanodisk arrays and gold nanoparticles. The large-scale nanostructures were fabricated by laser interference lithography technique. The detecting optical signal-extinction spectra of the system were monitored by UV-visible spectrophotometry. The 3D finitedifference time-domain simulation was used to observe the plasmonic interaction of the sensing system. The platform exhibits an exceptionally large turn-on signal by a 120 nm red shift of the localized surface plasmonic resonance peak, results in the limit detection of 140 pM. The centimeter-scale localized surface plasmon resonance nanostructures combined with turn-on design scheme would offer a promising sensor-on-chip biosensing platform.
Keywords: insulin sensing, localized surface plasmon, plasmonic interaction
Mots-clés : nanostructure.
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     author = {Thanh Thi Van Nguyen},
     title = {A plasmonic turn-on insulin sensing platform on centimeter scale nanostructure arrays},
     journal = {Nanosistemy: fizika, himi\^a, matematika},
     pages = {300--306},
     publisher = {mathdoc},
     volume = {15},
     number = {2},
     year = {2024},
     language = {en},
     url = {http://geodesic.mathdoc.fr/item/NANO_2024_15_2_a15/}
}
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Thanh Thi Van Nguyen. A plasmonic turn-on insulin sensing platform on centimeter scale nanostructure arrays. Nanosistemy: fizika, himiâ, matematika, Tome 15 (2024) no. 2, pp. 300-306. http://geodesic.mathdoc.fr/item/NANO_2024_15_2_a15/