Additive effects of green LED light and cerium oxide nanoparticles on the planarian's regeneration
Nanosistemy: fizika, himiâ, matematika, Tome 12 (2021) no. 2, pp. 175-181
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Nanotechnology makes it possible to design advanced materials being able to effectively modulate radiation effects on a cell, depending on the radiation intensity, wavelength, and type. Today, one of the most promising UV and X-ray protective biomaterials is nanocrystalline cerium oxide (CeO$_2$), which has a unique redox activity due to its surface reducibility. Meanwhile, the modulating properties of CeO$_2$ nanoparticles when the cells are exposed to visible light remain completely unexplored. Here, we analyzed the impact of CeO$_2$ nanoparticles on the process of planarian regeneration after exposure to low-intensity green LED light. It was found that a one-time exposure (10 or 25 min) of regenerating planarians with low-intensity green light reduced head blastema growth rate by up to 20%. At the same time, the preliminary treatment of planaria with CeO$_2$ nanoparticles in nanomolar concentrations (10 – 11 M) ensures the restoration of the neoblasts activity and a significant acceleration of blastema regeneration. Thus, we have firstly demonstrated that the planarian regeneration process can be promoted by cerium oxide nanoparticles even under adverse action of low-intensity green light radiation.
Keywords:
cerium oxide nanoparticles, green LED, planarian regeneration.
@article{NANO_2021_12_2_a6,
author = {A. M. Ermakov and K. A. Kamenskikh and A. L. Popov and O. N. Ermakova and V. A. Afanasyeva and V. K. Ivanov},
title = {Additive effects of green {LED} light and cerium oxide nanoparticles on the planarian's regeneration},
journal = {Nanosistemy: fizika, himi\^a, matematika},
pages = {175--181},
year = {2021},
volume = {12},
number = {2},
language = {en},
url = {http://geodesic.mathdoc.fr/item/NANO_2021_12_2_a6/}
}
TY - JOUR AU - A. M. Ermakov AU - K. A. Kamenskikh AU - A. L. Popov AU - O. N. Ermakova AU - V. A. Afanasyeva AU - V. K. Ivanov TI - Additive effects of green LED light and cerium oxide nanoparticles on the planarian's regeneration JO - Nanosistemy: fizika, himiâ, matematika PY - 2021 SP - 175 EP - 181 VL - 12 IS - 2 UR - http://geodesic.mathdoc.fr/item/NANO_2021_12_2_a6/ LA - en ID - NANO_2021_12_2_a6 ER -
%0 Journal Article %A A. M. Ermakov %A K. A. Kamenskikh %A A. L. Popov %A O. N. Ermakova %A V. A. Afanasyeva %A V. K. Ivanov %T Additive effects of green LED light and cerium oxide nanoparticles on the planarian's regeneration %J Nanosistemy: fizika, himiâ, matematika %D 2021 %P 175-181 %V 12 %N 2 %U http://geodesic.mathdoc.fr/item/NANO_2021_12_2_a6/ %G en %F NANO_2021_12_2_a6
A. M. Ermakov; K. A. Kamenskikh; A. L. Popov; O. N. Ermakova; V. A. Afanasyeva; V. K. Ivanov. Additive effects of green LED light and cerium oxide nanoparticles on the planarian's regeneration. Nanosistemy: fizika, himiâ, matematika, Tome 12 (2021) no. 2, pp. 175-181. http://geodesic.mathdoc.fr/item/NANO_2021_12_2_a6/