Geodesic
Pvp-stabilized tungsten oxide nanoparticles (WO$_3$) nanoparticles cause hemolysis of human erythrocytes in a dose-dependent manner
Nanosistemy: fizika, himiâ, matematika, Tome 10 (2019) no. 2, pp. 199-205

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Tungsten oxide nanoparticles (WO$_3$ NPs) are increasingly being considered as a promising material for biomedical applications. However, toxicological information on their effect on red blood cells (RBCs) remains very scarce. In this study, we examined the toxicity of PVP-stabilized tungsten oxide nanoparticles against human RBCs. Optical microscopy and spectrophotometry data showed that WO3 NPs induce hemolytic activity. This effect is probably attributed to the direct interaction of the nanoparticles with the RBCs, resulting in the oxidative stress, membrane injury, and subsequent hemolysis.
Keywords: tungsten oxide nanoparticles, human erythrocytes, hemolysis. 
@article{NANO_2019_10_2_a11,
     author = {A. L. Popov and I. V. Savintseva and N. R. Popova and T. O. Shekunova and O. S. Ivanova and A. B. Shcherbakov and D. A. Kozlov and V. K. Ivanov},
     title = {Pvp-stabilized tungsten oxide nanoparticles {(WO}$_3$) nanoparticles cause hemolysis of human erythrocytes in a dose-dependent manner},
     journal = {Nanosistemy: fizika, himi\^a, matematika},
     pages = {199--205},
     publisher = {mathdoc},
     volume = {10},
     number = {2},
     year = {2019},
     language = {en},
     url = {http://geodesic.mathdoc.fr/item/NANO_2019_10_2_a11/}
}
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AU  - T. O. Shekunova
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AU  - A. B. Shcherbakov
AU  - D. A. Kozlov
AU  - V. K. Ivanov
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%A D. A. Kozlov
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%J Nanosistemy: fizika, himiâ, matematika
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A. L. Popov; I. V. Savintseva; N. R. Popova; T. O. Shekunova; O. S. Ivanova; A. B. Shcherbakov; D. A. Kozlov; V. K. Ivanov. Pvp-stabilized tungsten oxide nanoparticles (WO$_3$) nanoparticles cause hemolysis of human erythrocytes in a dose-dependent manner. Nanosistemy: fizika, himiâ, matematika, Tome 10 (2019) no. 2, pp. 199-205. http://geodesic.mathdoc.fr/item/NANO_2019_10_2_a11/