Geodesic
PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of NCTC L929 mouse fibroblasts via induction of intracellular oxidative stress
Nanosistemy: fizika, himiâ, matematika, Tome 10 (2019) no. 1, pp. 92-101
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In this study, photochromic PVP-stabilized tungsten oxide nanoparticles (WO$_{3-x}$ NPs) were shown to exhibit a dose-dependent cytotoxic effect on mouse fibroblasts in vitro. WO$_{3-x}$ NPs reduce viability and proliferative activity of the cells via induction of intracellular oxidative stress leading to apoptosis and cell death. WO$_{3-x}$ NPs modulate the mRNA expression of a wide range of genes responsible for oxidative stress and the cell redox-system.
Keywords: tungsten oxide nanoparticles, cytotoxicity, fibroblasts.
Mots-clés : apoptosis 
@article{NANO_2019_10_1_a10,
     author = {A. L. Popov and A. M. Ermakov and T. O. Shekunova and A. B. Shcherbakov and O. N. Ermakova and O. S. Ivanova and N. R. Popova and A. Ye. Baranchikov and V. K. Ivanov},
     title = {PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of {NCTC} {L929} mouse fibroblasts via induction of intracellular oxidative stress},
     journal = {Nanosistemy: fizika, himi\^a, matematika},
     pages = {92--101},
     year = {2019},
     volume = {10},
     number = {1},
     language = {en},
     url = {http://geodesic.mathdoc.fr/item/NANO_2019_10_1_a10/}
}
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AU  - A. M. Ermakov
AU  - T. O. Shekunova
AU  - A. B. Shcherbakov
AU  - O. N. Ermakova
AU  - O. S. Ivanova
AU  - N. R. Popova
AU  - A. Ye. Baranchikov
AU  - V. K. Ivanov
TI  - PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of NCTC L929 mouse fibroblasts via induction of intracellular oxidative stress
JO  - Nanosistemy: fizika, himiâ, matematika
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%A A. M. Ermakov
%A T. O. Shekunova
%A A. B. Shcherbakov
%A O. N. Ermakova
%A O. S. Ivanova
%A N. R. Popova
%A A. Ye. Baranchikov
%A V. K. Ivanov
%T PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of NCTC L929 mouse fibroblasts via induction of intracellular oxidative stress
%J Nanosistemy: fizika, himiâ, matematika
%D 2019
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A. L. Popov; A. M. Ermakov; T. O. Shekunova; A. B. Shcherbakov; O. N. Ermakova; O. S. Ivanova; N. R. Popova; A. Ye. Baranchikov; V. K. Ivanov. PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of NCTC L929 mouse fibroblasts via induction of intracellular oxidative stress. Nanosistemy: fizika, himiâ, matematika, Tome 10 (2019) no. 1, pp. 92-101. http://geodesic.mathdoc.fr/item/NANO_2019_10_1_a10/