Geodesic
Synthesis and characterization of neomycin functionalized chitosan stabilized silver nanoparticles and study its antimicrobial activity
Nanosistemy: fizika, himiâ, matematika, Tome 7 (2016) no. 4, pp. 759-764

Voir la notice de l'article provenant de la source Math-Net.Ru

A simple green method was developed for the synthesis of silver nanoparticles in the presence of a neomycin-functionalized chitosan as stabilizing agent using a fresh lemon juice as green reducing agent. The stabilizing agent was synthesized based on the Schiff base formation reaction between the chitosan dialdehyde and neomycin antibiotic in 0.05 mM at pH 7.0. The combined form of neomycin antibiotic with chitosan can be used as stabilizing agent for silver nanoparticles (AgNPs) synthesized by a biogenic method using lemon juice as a green reducing agent. The neomycin functionalized chitosan stabilized AgNPs were characterized by various analytical techniques, including UV-Visible spectra studies, FTIR, XRD and SEM. The antimicrobial activity of these composite was tested against human pathogenic Gram-positive and Gram-negative bacteria. The synergetic effect of the neomycin functionalized chitosan protected silver nanoparticles was tested against various drug resistant microorganisms. These chitosan derivatives can be used in combination with an antibacterial agent to treat and inhibit a resistant bacterial infection or the growth of resistant bacterial infection.
Keywords: lemom juice, neomycin, antimicrobial activity.
Mots-clés : silver nanoparticles, chitosan 
@article{NANO_2016_7_4_a36,
     author = {R. K. Preethika and R. Ramya and M. Ganesan and S. Nagaraj and K. Pandian},
     title = {Synthesis and characterization of neomycin functionalized chitosan stabilized silver nanoparticles and study its antimicrobial activity},
     journal = {Nanosistemy: fizika, himi\^a, matematika},
     pages = {759--764},
     publisher = {mathdoc},
     volume = {7},
     number = {4},
     year = {2016},
     language = {en},
     url = {http://geodesic.mathdoc.fr/item/NANO_2016_7_4_a36/}
}
TY  - JOUR
AU  - R. K. Preethika
AU  - R. Ramya
AU  - M. Ganesan
AU  - S. Nagaraj
AU  - K. Pandian
TI  - Synthesis and characterization of neomycin functionalized chitosan stabilized silver nanoparticles and study its antimicrobial activity
JO  - Nanosistemy: fizika, himiâ, matematika
PY  - 2016
SP  - 759
EP  - 764
VL  - 7
IS  - 4
PB  - mathdoc
UR  - http://geodesic.mathdoc.fr/item/NANO_2016_7_4_a36/
LA  - en
ID  - NANO_2016_7_4_a36
ER  - 
%0 Journal Article
%A R. K. Preethika
%A R. Ramya
%A M. Ganesan
%A S. Nagaraj
%A K. Pandian
%T Synthesis and characterization of neomycin functionalized chitosan stabilized silver nanoparticles and study its antimicrobial activity
%J Nanosistemy: fizika, himiâ, matematika
%D 2016
%P 759-764
%V 7
%N 4
%I mathdoc
%U http://geodesic.mathdoc.fr/item/NANO_2016_7_4_a36/
%G en
%F NANO_2016_7_4_a36
R. K. Preethika; R. Ramya; M. Ganesan; S. Nagaraj; K. Pandian. Synthesis and characterization of neomycin functionalized chitosan stabilized silver nanoparticles and study its antimicrobial activity. Nanosistemy: fizika, himiâ, matematika, Tome 7 (2016) no. 4, pp. 759-764. http://geodesic.mathdoc.fr/item/NANO_2016_7_4_a36/