Geodesic
Unrestrained reciprocal space refinement of macromolecular structures as a~tool to indicate alternative conformations
Matematičeskaâ biologiâ i bioinformatika, Tome 3 (2008) no. 2, pp. 50-59.

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The detection of side chains in protein molecules that are present in crystal in alternative conformations is a laborious part of macromolecule structure determination by X-ray analysis. In our work we show, that significant changes of atom coordinates during X-ray refinement without stereochemical restraints may indicate the presence of alternative conformations. 
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O. V. Sobolev; V. Yu. Lunin. Unrestrained reciprocal space refinement of macromolecular structures as a~tool to indicate alternative conformations. Matematičeskaâ biologiâ i bioinformatika, Tome 3 (2008) no. 2, pp. 50-59. http://geodesic.mathdoc.fr/item/MBB_2008_3_2_a2/

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