Geodesic
Electrochemical aptasensor for detection of lung cancer tumor markers in blood plasma
Žurnal Sibirskogo federalʹnogo universiteta. Matematika i fizika, Tome 17 (2024) no. 6, pp. 761-768

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The study investigates the possibility of diagnosing lung cancer through the simultaneous detection of six tumor biomarkers of this disease (CYFRA21-1, EpCAM, PLAUR, LIFR, ProGRP, and CEA) in blood plasma. The levels of these proteins in blood plasma were determined using square-wave voltammetry with multiplexed electrochemical chips modified with DNA aptamers. The results obtained in the study demonstrated the capability of the multiplex electrochemical aptasensor to simultaneously detect in blood plasma such traditionally used lung cancer tumor markers as CYFRA21-1, EpCAM, PLAUR, LIFR, ProGRP, and CEA.
Keywords: aptamers, lung cancer, electrochemical aptasensor, blood plasma tumor biomarkers. 
@article{JSFU_2024_17_6_a7,
     author = {Yuri E. Glazyrin and Galina S. Zamay and Anna S. Kichkailo and Tatiana N. Zamay and Yuri S. Pats and Sergei S. Zamay and Kirill A. Lukyanenko and Olga S. Kolovskaya},
     title = {Electrochemical aptasensor for detection of lung cancer tumor markers in blood plasma},
     journal = {\v{Z}urnal Sibirskogo federalʹnogo universiteta. Matematika i fizika},
     pages = {761--768},
     publisher = {mathdoc},
     volume = {17},
     number = {6},
     year = {2024},
     language = {en},
     url = {http://geodesic.mathdoc.fr/item/JSFU_2024_17_6_a7/}
}
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AU  - Kirill A. Lukyanenko
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%0 Journal Article
%A Yuri E. Glazyrin
%A Galina S. Zamay
%A Anna S. Kichkailo
%A Tatiana N. Zamay
%A Yuri S. Pats
%A Sergei S. Zamay
%A Kirill A. Lukyanenko
%A Olga S. Kolovskaya
%T Electrochemical aptasensor for detection of lung cancer tumor markers in blood plasma
%J Žurnal Sibirskogo federalʹnogo universiteta. Matematika i fizika
%D 2024
%P 761-768
%V 17
%N 6
%I mathdoc
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Yuri E. Glazyrin; Galina S. Zamay; Anna S. Kichkailo; Tatiana N. Zamay; Yuri S. Pats; Sergei S. Zamay; Kirill A. Lukyanenko; Olga S. Kolovskaya. Electrochemical aptasensor for detection of lung cancer tumor markers in blood plasma. Žurnal Sibirskogo federalʹnogo universiteta. Matematika i fizika, Tome 17 (2024) no. 6, pp. 761-768. http://geodesic.mathdoc.fr/item/JSFU_2024_17_6_a7/