Impact of osmotic pressure on cancer cells in a three-dimensional cellular lattice and cell spheroid
Izvestiya VUZ. Applied Nonlinear Dynamics, Tome 29 (2021) no. 4, pp. 559-570
The purpose of this work is to study the peculiarities of external influence, namely osmotic pressure, on cancer cells. Methods. For this purpose, spatially distributed systems describing the dynamics of a three-dimensional cell lattice, a cell spheroid, and a cell surface have been considered. The studied models are based on the basic principles of hydrodynamics, and their numerical simulation has been performed using a modified Euler method. Results. The paper proposes three-dimensional models to study the dynamics of cancer cells in the epidermal layer of the skin; the models include the possibility of adding additional pressure and changing it with a single parameter. It is shown that it is possible to achieve a slowdown of cancer cell growth in all considered models at certain values of osmotic pressure.
Keywords:
cancer cells, cellular lattice, cell spheroid, self-organizing, osmotic pressure, logistic growth.
@article{IVP_2021_29_4_a6,
author = {N. I. Semenova and V. V. Tuchin},
title = {Impact of osmotic pressure on cancer cells in a three-dimensional cellular lattice and cell spheroid},
journal = {Izvestiya VUZ. Applied Nonlinear Dynamics},
pages = {559--570},
year = {2021},
volume = {29},
number = {4},
language = {ru},
url = {http://geodesic.mathdoc.fr/item/IVP_2021_29_4_a6/}
}
TY - JOUR AU - N. I. Semenova AU - V. V. Tuchin TI - Impact of osmotic pressure on cancer cells in a three-dimensional cellular lattice and cell spheroid JO - Izvestiya VUZ. Applied Nonlinear Dynamics PY - 2021 SP - 559 EP - 570 VL - 29 IS - 4 UR - http://geodesic.mathdoc.fr/item/IVP_2021_29_4_a6/ LA - ru ID - IVP_2021_29_4_a6 ER -
%0 Journal Article %A N. I. Semenova %A V. V. Tuchin %T Impact of osmotic pressure on cancer cells in a three-dimensional cellular lattice and cell spheroid %J Izvestiya VUZ. Applied Nonlinear Dynamics %D 2021 %P 559-570 %V 29 %N 4 %U http://geodesic.mathdoc.fr/item/IVP_2021_29_4_a6/ %G ru %F IVP_2021_29_4_a6
N. I. Semenova; V. V. Tuchin. Impact of osmotic pressure on cancer cells in a three-dimensional cellular lattice and cell spheroid. Izvestiya VUZ. Applied Nonlinear Dynamics, Tome 29 (2021) no. 4, pp. 559-570. http://geodesic.mathdoc.fr/item/IVP_2021_29_4_a6/