Geodesic
Feature of simultaneous influence of excitatory synaptic currents on a neuron with differential responses
Izvestiya VUZ. Applied Nonlinear Dynamics, Tome 23 (2015) no. 2, pp. 47-56.

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The simultaneous influence of excitatory synaptic stimuli (the tonic AMPA and NMDA currents) on the neuron model with response differentiation is studied. It is shown that different types of neuron activity (rest state, low frequency or high frequency firing) are observed depending on the conductance of the AMPA and NMDA receptors. It is found that for the certain parameters values if both types of receptors are activated simultaneously, it is possible to obtain maximal frequency to be approximately 20% greater than that with the NMDA current alone. Thus, we confirm the major role of NMDA receptors in the appearance of high-frequency firing and conclude that AMPAR activation may further significantly increase the frequency. The dynamical mechanism of such frequency growth is explained in the framework of phase plain evolution.
Keywords: AMPA, NMDA, Neuron, excitatory synaptic current, AMPA, NMDA, response differentiation. 
@article{IVP_2015_23_2_a3,
     author = {D. G. Zakharov and D. V. Kasatkin and S. Yu. Kirillov and A. S. Kuznetsov},
     title = {Feature of simultaneous influence of excitatory synaptic currents on a neuron with differential responses},
     journal = {Izvestiya VUZ. Applied Nonlinear Dynamics},
     pages = {47--56},
     publisher = {mathdoc},
     volume = {23},
     number = {2},
     year = {2015},
     language = {ru},
     url = {http://geodesic.mathdoc.fr/item/IVP_2015_23_2_a3/}
}
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D. G. Zakharov; D. V. Kasatkin; S. Yu. Kirillov; A. S. Kuznetsov. Feature of simultaneous influence of excitatory synaptic currents on a neuron with differential responses. Izvestiya VUZ. Applied Nonlinear Dynamics, Tome 23 (2015) no. 2, pp. 47-56. http://geodesic.mathdoc.fr/item/IVP_2015_23_2_a3/