Geodesic
Bioinformatics and search of reading frame shifts in genes
Informacionnye tehnologii i vyčislitelnye sistemy, no. 1 (2010), pp. 3-23

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The definition of a phase shift of triplet periodicity (TP) is introduced. The mathematical algorithm for detection of a phase shift of TP in nucleotide sequences has been developed. The gene sequences from the Kegg-46 data bank were have been analyzed to search for genes with TP phase shifts. The presence of a phase shift of triplet periodicity for 27417 genes (0.7% from the total number of genes in the Kegg-46 data bank) has been demonstrated. We show that TP phase shifts are determined by the shifts of a reading frame in genes. The connection between phase shifts of TP and frame shifts in genes is discussed.
Keywords: triplet periodicity, open reading frame, shifts. 
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     author = {M. A. Korotkova and E. V. Korotkov},
     title = {Bioinformatics and search of reading frame shifts in genes},
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M. A. Korotkova; E. V. Korotkov. Bioinformatics and search of reading frame shifts in genes. Informacionnye tehnologii i vyčislitelnye sistemy, no. 1 (2010), pp. 3-23. http://geodesic.mathdoc.fr/item/ITVS_2010_1_a0/