Initial Layer Analysis for a Linkage Density in Cell Adhesion Mechanisms
ESAIM. Proceedings, Tome 62 (2018), pp. 108-122
In this paper we present a non local age structured equation involved in cell motility modeling [5, 9, 11]. It describes the evolution of a density of linkages of a point submitted to adhesion. It depends on an asymptotic parameter ɛ representing the characteristic age of linkages. Here we introduce a new initial layer term in the asymptotic expansion with respect to ɛ. This improves error estimates obtained in [5]. Moreover, we study the convergence of the time derivative of this density and show how a singular term appears when ɛ goes to zero. We show convergence, in the tight topology of measures, to the time derivative of the limit solution and a Dirac mass supported on the initial half-axis. In order to illustrate these results, numerical simulations are performed and compared to the asymptotic expansion for various values of ɛ.
@article{EP_2018_62_a9,
author = {Vuk Milisic},
title = {Initial {Layer} {Analysis} for a {Linkage} {Density} in {Cell} {Adhesion} {Mechanisms}},
journal = {ESAIM. Proceedings},
pages = {108--122},
year = {2018},
volume = {62},
doi = {10.1051/proc/201862108},
language = {en},
url = {http://geodesic.mathdoc.fr/articles/10.1051/proc/201862108/}
}
Vuk Milisic. Initial Layer Analysis for a Linkage Density in Cell Adhesion Mechanisms. ESAIM. Proceedings, Tome 62 (2018), pp. 108-122. doi: 10.1051/proc/201862108
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