Influence of Fibrinogen Deficiency on Clot Formation in Flow by Hybrid Model
Mathematical modelling of natural phenomena, Tome 10 (2015) no. 1, pp. 36-47.

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In this work we develop the 2D model suggested in [] in order to study the impact of fibrinogen concentration and the fibrin polymer production rate on clot growth in flow. The model is based on the method of Dissipative Particle Dynamics describing blood plasma flow and platelet suspension and on a system of partial differential equations describing blood coagulation regulatory network. We study the influence of parameters on clot development and on its final size.
DOI : 10.1051/mmnp/201510102

A. Tosenberger 1, 2 ; N. Bessonov 3 ; V. Volpert 1, 2

1 Institut Camille Jordan, UMR 5208 CNRS, University Lyon 1, 69622 Villeurbanne, France
2 INRIA Team Dracula, INRIA Antenne Lyon la Doua, 69603 Villeurbanne, France
3 Institute of Mechanical Engineering Problems, 199178 Saint Petersburg, Russia
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A. Tosenberger; N. Bessonov; V. Volpert. Influence of Fibrinogen Deficiency on Clot Formation in Flow by Hybrid Model. Mathematical modelling of natural phenomena, Tome 10 (2015) no. 1, pp. 36-47. doi : 10.1051/mmnp/201510102. http://geodesic.mathdoc.fr/articles/10.1051/mmnp/201510102/

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