Geodesic
Host Factors in Viral Life Cycles
G. Pérez-Vilaró1 ; J. Jungfleisch1 ; V. Saludes1 ; N. Scheller1 ; M. Giménez-Barcons1 ; J. Díez1
1 Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
Mathematical modelling of natural phenomena, Tome 7 (2012) no. 5, pp. 123-132 Cet article a éte moissonné depuis la source EDP Sciences

Voir la notice de l'article

Viruses are obligate intracellular parasites that rely on the host cell for expansion. With the development of global analyses techniques like transcriptomics, proteomics and siRNA library screening of complete cellular gene sets, a large range of host cell factors have been discovered that either support or restrict virus growth. Here we summarize some of the recent findings and focus our discussion on the hepatitis C virus and the human immunodeficiency virus, two major pathogens that threat global health. The identification of cellular proteins affecting multiple viruses points to the existence of central regulation nodes that might be exploited for both, a quantitative description of host-virus interactions within single infected cells and the development of novel, broad-spectrum antiviral drugs.
DOI : 10.1051/mmnp/20127509

G. Pérez-Vilaró 1 ; J. Jungfleisch 1 ; V. Saludes 1 ; N. Scheller 1 ; M. Giménez-Barcons 1 ; J. Díez 1

1 Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain 
@article{10_1051_mmnp_20127509,
     author = {G. P\'erez-Vilar\'o and J. Jungfleisch and V. Saludes and N. Scheller and M. Gim\'enez-Barcons and J. D{\'\i}ez},
     title = {Host {Factors} in {Viral} {Life} {Cycles}},
     journal = {Mathematical modelling of natural phenomena},
     pages = {123--132},
     year = {2012},
     volume = {7},
     number = {5},
     doi = {10.1051/mmnp/20127509},
     language = {en},
     url = {http://geodesic.mathdoc.fr/articles/10.1051/mmnp/20127509/}
}
TY  - JOUR
AU  - G. Pérez-Vilaró
AU  - J. Jungfleisch
AU  - V. Saludes
AU  - N. Scheller
AU  - M. Giménez-Barcons
AU  - J. Díez
TI  - Host Factors in Viral Life Cycles
JO  - Mathematical modelling of natural phenomena
PY  - 2012
SP  - 123
EP  - 132
VL  - 7
IS  - 5
UR  - http://geodesic.mathdoc.fr/articles/10.1051/mmnp/20127509/
DO  - 10.1051/mmnp/20127509
LA  - en
ID  - 10_1051_mmnp_20127509
ER  - 
%0 Journal Article
%A G. Pérez-Vilaró
%A J. Jungfleisch
%A V. Saludes
%A N. Scheller
%A M. Giménez-Barcons
%A J. Díez
%T Host Factors in Viral Life Cycles
%J Mathematical modelling of natural phenomena
%D 2012
%P 123-132
%V 7
%N 5
%U http://geodesic.mathdoc.fr/articles/10.1051/mmnp/20127509/
%R 10.1051/mmnp/20127509
%G en
%F 10_1051_mmnp_20127509
G. Pérez-Vilaró; J. Jungfleisch; V. Saludes; N. Scheller; M. Giménez-Barcons; J. Díez. Host Factors in Viral Life Cycles. Mathematical modelling of natural phenomena, Tome 7 (2012) no. 5, pp. 123-132. doi: 10.1051/mmnp/20127509

[1] P. Ahlquist Nat. Rev. Microbiol. 2006 371 382

[2] L. Ajamian, L. Abrahamyan, M. Milev, P.V. Ivanov, A.E. Kulozik, N.H. Gehring, A.J. Mouland RNA 2008 914 927

[3] I. Alves-Rodrigues, A. Mas, J. Díez J.Virol. 2007 4378 4380

[4] P.C. Angeletti, K. Kim, F.J. Fernandes, P.F. Lambert J. Virol. 2002 3350 3358

[5] Y. Ariumi, M. Kuroki, K. Abe, H. Dansako, M. Ikeda, T. Wakita, N. Kato J. Virol. 2007 13922 13926

[6] Y. Ariumi, M. Kuroki, Y. Kushima, K. Osugi, M. Hijikata, M. Maki, M. Ikeda, N. Kato J. Virol. 2011 6882 6892

[7] S. Bandyopadhyay, R.C. Friedman, R.T. Marquez, K. Keck, B. Kong, M.S. Icardi, K.E. Brown, C.B. Burge, W.N. Schmidt, Y. Wang, A.P. Mccaffrey J. Infect. Dis. 2011 1753 1762

[8] A.L. Brass, D.M. Dykxhoorn, Y. Benita, N. Yan, A. Engelman, R.J. Xavier, J. Lieberman, S.J. Elledge Science 2008 921 926

[9] F.D. Bushman, N. Malani, J. Fernandes, I. D’Orso, G. Cagney, T.L. Diamond, H. Zhou, D.J. Hazuda, A.S. Espeseth, R. Konig, S. Bandyopadhyay, T. Ideker, S.P. Goff, N.J. Krogan, A.D. Frankel, J.A. Young, S.K. Chanda PLoS Pathog. 2009

[10] J. Coller, R. Parker Annu. Rev. Biochem. 2004 861 890

[11] Y.L. Chiu, T.M. Rana Mol. Cell 2002 549 561

[12] H. Dahari, R.M. Ribeiro, C.M. Rice, A.S. Perelson J. Virol. 2007 750 760

[13] K.U. Dee, M.L. Shuler Biotechnol. Bioeng. 1997 468 490

[14] J. Diez, M. Ishikawa, M. Kaido, P. Ahlquist Proc. Natl .Acad. Sci. U.S.A 2000 3913

[15] J.D. Dougherty, J.P. White, R.E. Lloyd J. Virol. 2011 64 75

[16] C.J. Echeverri, P.A. Beachy, B. Baum, M. Boutros, F. Buchholz, S.K. Chanda, J. Downward, J. Ellenberg, A.G. Fraser, N. Hacohen, W.C. Hahn, A.L. Jackson, A. Kiger, P.S. Linsley, L. Lum, Y. Ma, B. Mathey-Prevot, D.E. Root, D.M. Sabatini, J. Taipale, N. Perrimon, R. Bernards Nat. Methods 2006 777 779

[17] M.M. Emara, M.A. Brinton Proc. Natl. Acad. Sci. U.S.A. 2007 9041 9046

[18] M.M. Emara, H. Liu, W.G. Davis, M.A. Brinton J. Virol. 2008 10657 10670

[19] S.L. Erickson, J. Lykke-Andersen J. Cell Sci. 2011 293 297

[20] A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, C.C. Mello Nature 1998 806 811

[21] V. Fontanes, S. Raychaudhuri, A. Dasgupta Virology 2009 82 90

[22] M.T. Franze De Fernandez, L. Eoyang, J.T. August Nature 1968 588

[23] B.L. Gancarz, L. Hao, Q. He, M.A. Newton, P. Ahlquist PLoS ONE 2011

[24] D.M. Gelperin, M.A. White, M.L. Wilkinson, Y. Kon, L.A. Kung, K.J. Wise, N. Lopez-Hoyo, L. Jiang, S. Piccirillo, H. Yu, M. Gerstein, M.E. Dumont, E.M. Phizicky, M. Snyder, E.J. Grayhack Genes Dev . 2005 2816 2826

[25] S. Ghaemmaghami, W.-K. Huh, K. Bower, R.W. Howson, A. Belle, N. Dephoure, E.K. O’Shea, J.S. Weissman Nature 2003 737 741

[26] M. Giménez-Barcons, J. Díez Microb. Cell Fact. 2011

[27] J.I. Henke, D. Goergen, J. Zheng, Y. Song, C.G. Schuttler, C. Fehr, C. Junemann, M. Niepmann EMBO J. 2008 3300 3310

[28] S.C. Hensel, J.B. Rawlings, J. Yin Bull. Math. Biol. 2009 1671 1692

[29] W. Hou, Q. Tian, J. Zheng, H.L. Bonkovsky Hepatology 2010 1494 1504

[30] J. Huang, F. Wang, E. Argyris, K. Chen, Z. Liang, H. Tian, W. Huang, K. Squires, G. Verlinghieri, H. Zhang Nat. Med. 2007 1241 1247

[31] W.-K. Huh, J.V. Falvo, L.C. Gerke, A.S. Carroll, R.W. Howson, J.S. Weissman, E.K. O’Shea Nature 2003 686 691

[32] M. Ishaq, J. Hu, X. Wu, Q. Fu, Y. Yang, Q. Liu, D. Guo Mol. Biotechnol. 2008 231 238

[33] H. Ishida, T. Tatsumi, A. Hosui, T. Nawa, T. Kodama, S. Shimizu, H. Hikita, N. Hiramatsu, T. Kanto, N. Hayashi, T. Takehara Biochem Biophys. Res. Commun. 2011 92 97

[34] I.M. Jacobson, J.G. Mchutchison, G. Dusheiko, A.M. Di Bisceglie, K.R. Reddy, N.H. Bzowej, P. Marcellin, A.J. Muir, P. Ferenci, R. Flisiak, J. George, M. Rizzetto, D. Shouval, R. Sola, R.A. Terg, E.M. Yoshida, N. Adda, L. Bengtsson, A.J. Sankoh, T.L. Kieffer, S. George, R.S. Kauffman, S. Zeuzem N. Engl. J. Med. 2011 2405 2416

[35] M. Janda, P. Ahlquist Cell 1993 961 970

[36] R.K. Jangra, M. Yi, S.M. Lemon J. Virol. 2010 6810 6824

[37] Y. Jiang, E. Serviene, J. Gal, T. Panavas, P.D. Nagy J. Virol. 2006 7394 7404

[38] C.L. Jopling, M. Yi, A.M. Lancaster, S.M. Lemon, P. Sarnow Science 2005 1577 1581

[39] A. Khong, E. Jan J. Virol. 2011 1439 1451

[40] R. Konig, Y. Zhou, D. Elleder, T.L. Diamond, G.M. Bonamy, J.T. Irelan, C.Y. Chiang, B.P. Tu, P.D. De Jesus, C.E. Lilley, S. Seidel, A.M. Opaluch, J.S. Caldwell, M.D. Weitzman, K.L. Kuhen, S. Bandyopadhyay, T. Ideker, A.P. Orth, L.J. Miraglia, F.D. Bushman, J.A. Young, S.K. Chanda Cell 2008 49 60

[41] M. Korf, D. Jarczak, C. Beger, M.P. Manns, M. Kruger J. Hepatol. 2005 225 234

[42] D.B. Kushner, B.D. Lindenbach, V.Z. Grdzelishvili, A.O. Noueiry, S.M. Paul, P. Ahlquist Proc. Natl. Acad. Sci. U.S.A. 2003 15764 15769

[43] R.C. Lee, R.L. Feinbaum, V. Ambros Cell 1993 843 854

[44] Q. Li, A.L. Brass, A. Ng, Z. Hu, R.J. Xavier, T.J. Liang, S.J. Elledge Proc. Natl. Acad. Sci. U.S.A. 2009 16410 16415

[45] W. Li, Y. Li, N. Kedersha, P. Anderson, M. Emara, K.M. Swiderek, G.T. Moreno, M.A. Brinton J. Virol. 2002 11989 12000

[46] K.I. Lim, T. Lang, V. Lam, J. Yin PLoS Comput. Biol. 2006

[47] X. Liu, T. Wang, T. Wakita, W. Yang Virology 2010 57 67

[48] M. Maeda, H. Sawa, M. Tobiume, K. Tokunaga, H. Hasegawa, T. Ichinohe, T. Sata, M. Moriyama, W.W. Hall, T. Kurata, H. Takahashi Microbes Infect. 2006 2647 2656

[49] G. Maga, F. Falchi, M. Radi, L. Botta, G. Casaluce, M. Bernardini, H. Irannejad, F. Manetti, A. Garbelli, A. Samuele, S. Zanoli, J.A. Este, E. Gonzalez, E. Zucca, S. Paolucci, F. Baldanti, J. De Rijck, Z. Debyser, M. Botta ChemMedChem. 2011 1371 1389

[50] K.L. Martin, M. Johnson, R.T. D’Aquila J. Virol. 2011 9314 9326

[51] A. Mas, I. Alves-Rodrigues, A. Noueiry, P. Ahlquist, J. Díez J.Virol. 2006 246

[52] S. Mnaimneh, A.P. Davierwala, J. Haynes, J. Moffat, W.-T. Peng, W. Zhang, X. Yang, J. Pootoolal, G. Chua, A. Lopez, M. Trochesset, D. Morse, N.J. Krogan, S.L. Hiley, Z. Li, Q. Morris, J. Grigull, N. Mitsakakis, C.J. Roberts, J.F. Greenblatt, C. Boone, C.A. Kaiser, B.J. Andrews, T.R. Hughes Cell 2004 31 44

[53] J. Nakabayashi J. Theor. Biol. 2012

[54] R. Nathans, C.Y. Chu, A.K. Serquina, C.C. Lu, H. Cao, T.M. Rana Mol. Cell 2009 696 709

[55] A.O. Noueiry, J. Chen, P. Ahlquist Proc. Natl. Acad. Sci. U.S.A. 2000 12985 12990

[56] A.O. Noueiry, J. Díez, S.P. Falk, J. Chen, P. Ahlquist Mol. Cell. Biol. 2003 4094 4106

[57] T. Panavas, P.D. Nagy Virology 2003 315 325

[58] T. Panavas, E. Serviene, J. Brasher, P.D. Nagy Proc. Natl. Acad. Sci. U.S.A. 2005 7326 7331

[59] V. Pantaleo, L. Rubino, M. Russo J. Virol. 2003 2116 2123

[60] A.B. Parsons, R. Geyer, T.R. Hughes, C. Boone Prog. Cell Cycle Res. 2003

[61] X. Peng, Y. Li, K.A. Walters, E.R. Rosenzweig, S.L. Lederer, L.D. Aicher, S. Proll, M.G. Katze BMC Genomics 2009

[62] G. Pérez-Vilaró, N. Scheller, V. Saludes, J. Díez J. Virol. 2012 8740 8749

[63] R. Persson, M. Hodges, B.D. King, A. Chen, K. Zeh, A.A. Levine J. Hepatol. 2012 S477

[64] F. Poordad, J. Mccone, B.R. Bacon, S. Bruno, M.P. Manns, M.S. Sulkowski, I.M. Jacobson, K.R. Reddy, Z.D. Goodman, N. Boparai, M.J. Dinubile, V. Sniukiene, C.A. Brass, J.K. Albrecht, J.P. Bronowicki N. Engl. J. Med. 2011 1195 1206

[65] B.D. Price, L.D. Eckerle, L.A. Ball, K.L. Johnson J. Virol. 2005 495 502

[66] B.D. Price, R.R. Rueckert, P. Ahlouist Proc. Natl. Acad. Sci. U.S.A. 1996 9465 9470

[67] V. Raghavan, P.S. Malik, N.R. Choudhury, S.K. Mukherjee J. Virol. 2004 2405 2413

[68] G. Randall, M. Panis, J.D. Cooper, T.L. Tellinghuisen, K.E. Sukhodolets, S. Pfeffer, M. Landthaler, P. Landgraf, S. Kan, B.D. Lindenbach, M. Chien, D.B. Weir, J.J. Russo, J. Ju, M.J. Brownstein, R. Sheridan, C. Sander, M. Zavolan, T. Tuschl, C.M. Rice Proc. Natl. Acad. Sci. U.S.A. 2007 12884 12889

[69] B. Reddy, J. Yin AIDS Res Hum. Retroviruses 1999 273 283

[70] A. Rivas-Aravena, P. Ramdohr, M. Vallejos, F. Valiente-Echeverria, V. Dormoy-Raclet, F. Rodriguez, K. Pino, C. Holzmann, J.P. Huidobro-Toro, I.E. Gallouzi, M. Lopez-Lastra Virology 2009 178 185

[71] N. Scheller, L.B. Mina, R.P. Galao, A. Chari, M. Giménez-Barcons, A. Noueiry, U. Fischer, A. Meyerhans, J. Díez Proc. Natl. Acad. Sci. U.S.A. 2009 13517 13522

[72] P. Sean, J.H. Nguyen, B.L. Semler Virology 2009 45 58

[73] K.E. Sherman, S.L. Flamm, N.H. Afdhal, D.R. Nelson, M.S. Sulkowski, G.T. Everson, M.W. Fried, M. Adler, H.W. Reesink, M. Martin, A.J. Sankoh, N. Adda, R.S. Kauffman, S. George, C.I. Wright, F. Poordad N. Engl. J. Med. 2011 1014 1024

[74] Y. Sidorenko, U. Reichl Biotechnol. Bioeng. 2004 1 14

[75] M. Sioud Methods Mol. Biol. 2011

[76] A. Spear, N. Sharma, J.B. Flanegan Virology 2008 280 291

[77] G. Sun, H. Li, X. Wu, M. Covarrubias, L. Scherer, K. Meinking, B. Luk, P. Chomchan, J. Alluin, A.F. Gombart, J.J. Rossi Nucleic Acids Res. 2012 2181 2196

[78] A.W. Tai, Y. Benita, L.F. Peng, S.S. Kim, N. Sakamoto, R.J. Xavier, R.T. Chung Cell Host Microbe 2009 298 307

[79] G. Tiscornia, O. Singer, M. Ikawa, I.M. Verma Proc. Natl. Acad. Sci. U.S.A. 2003 1844 1848

[80] R. Triboulet, B. Mari, Y.L. Lin, C. Chable-Bessia, Y. Bennasser, K. Lebrigand, B. Cardinaud, T. Maurin, P. Barbry, V. Baillat, J. Reynes, P. Corbeau, K.T. Jeang, M. Benkirane Science 2007 1579 1582

[81] A.M. Ward, K. Bidet, A. Yinglin, S.G. Ler, K. Hogue, W. Blackstock, J. Gunaratne, M.A. Garcia-Blanco RNA Biol. 2011 1173 1186

[82] J.P. White, R.E. Lloyd Trends Microbiol. 2012 175 183

[83] E.A. Winzeler, D.D. Shoemaker, A. Astromoff, H. Liang, K. Anderson, B. Andre, R. Bangham, R. Benito, J.D. Boeke, H. Bussey, A.M. Chu, C. Connelly, K. Davis, F. Dietrich, S.W. Dow, M. El Bakkoury, F. Foury, S.H. Friend, E. Gentalen, G. Giaever, J.H. Hegemann, T. Jones, M. Laub, H. Liao, N. Liebundguth, D.J. Lockhart, A. Lucau-Danila, M. Lussier, N. M’Rabet, P. Menard, M. Mittmann, C. Pai, C. Rebischung, J.L. Revuelta, L. Riles, C.J. Roberts, P. Ross-Macdonald, B. Scherens, M. Snyder, S. Sookhai-Mahadeo, R.K. Storms, S. V?Ronneau, M. Voet, G. Volckaert, T.R. Ward, R. Wysocki, G.S. Yen, K. Yu, K. Zimmermann, P. Philippsen, M. Johnston, R.W. Davis Science 1999 901 906

[84] H. Xia, Q. Mao, H.L. Paulson, B.L. Davidson Nat. Biotechnol. 2002 1006 1010

[85] M.L. Yeung, L. Houzet, V.S. Yedavalli, K.T. Jeang J. Biol. Chem. 2009 19463 19473

[86] Z. Yi, C. Fang, T. Pan, J. Wang, P. Yang, Z. Yuan Biochem. Biophys. Res. Commun. 2006 174 178

[87] S.F. Yu, P. Lujan, D.L. Jackson, M. Emerman, M.L. Linial PLoS Pathog. 2011

[88] K.-N. Zhao, I.H. Frazer J. Virol. 2002 3359 3364

[89] H. Zhou, M. Xu, Q. Huang, A.T. Gates, X.D. Zhang, J.C. Castle, E. Stec, M. Ferrer, B. Strulovici, D.J. Hazuda, A.S. Espeseth Cell Host Microbe 2008 495 504

Cité par Sources :